Journal Reviews

The Journal of Urology cover image.

Fluoxetine for refractory night wetting in children – is it safe and effective?

11 July 2023 | | Paediatric Urology | fluoxetine, nocturnal enuresis, safety, serotonin uptake inhibitors

Around 1-2% of teenagers above the age of 15 years and 2-6% of adults continue to wet the bed. Standard treatment often includes bladder advice, alarm therapy, desmopressin and anticholinergics. Tricyclic antidepressants (imipramine) can also be utilised. Unfortunately, most have...